IOX 1, JMJD demethylase inhibitor (TBI1426)
$130.00 – $518.00
JMJD demethylase inhibitor
SKU | Stock | SIZE (mg) | Price | Quantity | ||
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TBI1426-5MG | Yes | 5 MG | $130.00 | |||
TBI1426-25MG | Yes | 25 MG | $518.00 |
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Description
Product Details
Formal Name: 8-Hydroxy-5-quinolinecarboxylic acid
Alternate Names: 5-Carboxy-8HQ
Molecular Formula: C10H7NO3
Formula Weight: 189.17
CAS Number: 5852-78-8
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to 20 mg/ml).
Storage: RT
Stability: ≥ 1 year.
Applications
JMJD demethylase inhibitor
Functions
Inhibits the JMJD family of 2-oxoglutarate-dependent histone demethylases. IC50 = 0.12, 0.07, 0.2, 0.3, 0.6, and 1 μM for JMJD3, JMJD1A, JMJD2A, JMJD2E, JMJD2C and UTX respectively. A broad spectrum 2-oxoglutarate oxygenase inhibitor which may be used to study hypoxic signaling. Cell permeable
Application Procedures
First dissolved in DMSO (up to 20 mg/ml), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20° for up to 3 months.
Additional information
SIZE (mg) | 25 MG, 5 MG |
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