Luminespib, HSP90 inhibitor (TBI4672)
$81.00 – $261.00
HSP90 inhibitor
SKU | Stock | SIZE (mg) | Price | Quantity | ||
---|---|---|---|---|---|---|
TBI4672-5MG | Yes | 5 MG | $81.00 | |||
TBI4672-25MG | Yes | 25 MG | $261.00 |
- Description
- Terms
- Additional information
- Documents
- Reviews (0)
Description
Product Details
Formal Name: 5-(2,4-Dihydroxy-5-propan-2-ylphenyl)-N-ethyl-4-[4-(morpholin-4-ylmethyl)phenyl]-1,2-oxazole-3-carboxamide
Alternate Names: NVP-AUY922; VER-52296
Molecular Formula: C26H31N3O5
Formula Weight: 465.50
CAS Number: 747412-49-3
Purity: >99%
Formulation: powder
Solubility: Soluble in DMSO (up to 25 mg/ml)
Storage: -20°C
Stability: ≥ 1 year.
Applications
HSP90 inhibitor
Functions
Potent inhibitor (IC50 = 21 nM) of HSP90. It is active against various human tumor xenograft models acting via several processes including cytostasis, apoptosis, invasion, and angiogenesis. Luminespib enhances tumor susceptibility to T-cell-based immunotherapy by re-invigorating the cancer-immunity cycle in NANOG+ cancer cells. It also acts as a radiosensitizer against various tumor cells.
Application Procedures
First dissolved in DMSO (up to 25 mg/ml), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20°C for up to 2 months.
Additional information
SIZE (mg) | 25 MG, 5 MG |
---|
Be the first to review “Luminespib, HSP90 inhibitor (TBI4672)”
You must be logged in to post a review.
Reviews
There are no reviews yet.