Panobinostat, HDAC inhibitor (TBI2157)
$72.00 – $288.00
HDAC inhibitor
SKU | Stock | SIZE (mg) | Price | Quantity | ||
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TBI2157-5MG | Yes | 5 MG | $72.00 | |||
TBI2157-25MG | Yes | 25 MG | $288.00 |
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Description
Product Details
Formal Name: (E)-N-Hydroxy-3-(4-((2-(2-methyl-1H-indol-3-yl)ethylamino)methyl)phenyl)acrylamide
Alternate Names: LBH-589
Molecular Formula: C21H23N3O2
Formula Weight: 349.44
CAS Number: 404950-80-7
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to 100 mg/ml) or in Ethanol (up to 5 mg/ml with warming).
Storage: -20°C
Stability: ≥ 1 year.
Applications
HDAC inhibitor
Functions
A potent inhibitor of class I and II HDACs. Cotreatment with panobinostat and an HSP90 inhibitor caused synergistic apoptosis in human CML-BC and AML cells. A potent antimyeloma agent that overcomes drug resistance.
Application Procedures
First dissolved in DMSO (up to 100 mg/ml) or in Ethanol (up to 5 mg/ml with warming), then diluted to aqueous buffer. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.
Additional information
SIZE (mg) | 25 MG, 5 MG |
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