Fasnall HCl, Fatty acid synthase inhibitor (TBI1613)
$119.00 – $475.00
Fatty acid synthase inhibitor
SKU | Stock | SIZE (mg) | Price | Quantity | ||
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TBI1613-5MG | Yes | 5 MG | $119.00 | |||
TBI1613-25MG | Yes | 25 MG | $475.00 |
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Description
Product Details
Formal Name: 5,6-Dimethyl-N-[1-(phenylmethyl)-3-pyrrolidinyl]thieno[2,3-d]pyrimidin-4-amine benzenesulfonate hydrochloride
Molecular Formula: C19H22N4S HCl
Formula Weight: 374.93
CAS Number: 929978-58-5
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to 25 mg/ml) or in Water (up to 45 mg/ml)
Storage: -20°C
Stability: ≥ 1 year.
Applications
Fatty acid synthase inhibitor
Functions
A potent and selective fatty acid synthase (FASN) inhibitor acting via interfering with cofactor binding.
IC50s = 147 and 213 nM respectively for inhibition of acetate and glucose incorporation into total lipids in HepG2 cells. IC50=5.84 μM in an isolated enzyme assay. Displays potent antitumor activity in the MMTV-Neu HER2+ breast cancer model. Reduces HIV-1 virion production by 90% (EC50=213 nM).
Application Procedures
First dissolved in DMSO (up to 25 mg/ml) or in Water (up to 45 mg/ml), then diluted to aqueous buffer. Solutions in DMSO or distilled water may be stored at -20°C for up to 3 months.
Additional information
SIZE (mg) | 25 MG, 5 MG |
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