SMER3, E3 Ubiquitin ligase inhibitor (TBI1356)

Description

Product Details

Formal Name: 9H-Indeno[1,2-e][1,2,5]oxadiazolo[3,4-b]pyrazin-9-one

Molecular Formula: C₁₁H₄N₄O₂S

Formula Weight: 224.18

CAS Number: 67200-34-4

Purity: >98%

Formulation: powder

Solubility: Soluble in DMSO (up to 20 mg/ml).

Storage: RT

Stability: ≥ 2 years.

 

Applications

E3 Ubiquitin ligase inhibitor

 

Functions

Small Molecule Enhancer of Rapamycin 3 (SMER3) is a specific inhibitor if the ubiquitin E3 ligase SCFMET30 both in vitro and in vivo.

 

Application Procedures

First dissolved in DMSO (up to 20 mg/ml), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20° for up to 2 months.

Additional information

SIZE (mg)	25 MG, 5 MG

TBI1356_Data_Sheet