Pyr41, E1 UAE inhibitor (TBI1304)

Description

Product Details

Formal Name: 4-[4-(5-Nitro-furan-2-ylmethylene)-3,5-dioxo-pyrazolidin-1-yl]-benzoic acid ethyl ester

Molecular Formula: C₁₇H₁₃N₃O₇

Formula Weight: 371.31

CAS Number: 418805-02-4

Purity: >98%

Formulation: powder

Solubility: Soluble in DMSO (up to 25 mg/ml).

Storage: -20°C

Stability: ≥ 2 years.

 

Applications

E1 UAE inhibitor

 

Functions

Inhibits ubiquitin activating enzyme E1 (>60% inhibition at 10 µM) with little or no activity against E2 or E3.  Cell permeable

 

Application Procedures

First dissolved in DMSO (up to 25 mg/ml), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20° for up to 1 week.

Additional information

SIZE (mg)	25 MG, 5 MG

TBI1304_Data_Sheet