Deltamethrin, Calcineurin inhibitor; Displays neurotrophic activity (TBI3103)
$90.00 – $216.00
Calcineurin inhibitor; Displays neurotrophic activity
SKU | Stock | SIZE (mg) | Price | Quantity | ||
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TBI3103-5MG | Yes | 5 MG | $90.00 | |||
TBI3103-25MG | Yes | 25 MG | $216.00 |
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Description
Product Details
Formal Name: (S)-α-Cyano-3-phenoxybenzyl (1R, 3R)-3-(2,2-dibromovinyl)-2,2-dimethylcyclopropanecarboxylate
Alternate Names: Decamethrin
Molecular Formula: C22H19Br2NO3
Formula Weight: 505.20
CAS Number: 52918-63-5
Purity: >98%
Formulation: powder
Solubility: Soluble in DSMO (up to 50 mg/ml)
Storage: -20°C
Stability: ≥ 1 year.
Applications
Calcineurin inhibitor; Displays neurotrophic activity
Functions
Deltamethrin is reported to be an inhibitor of calcineurin (PP2B), IC50~100 pM but this activity has been disputed. Markedly enhances the expression of BDNF in cultured rat cortical neurons and displays neurotrophic effects. Produces antidepressant-like effects in mice. Blocks the spontaneous down-regulation of Nav1.8 sodium channels expressed in Xenopus oocytes.
Application Procedures
First dissolved in DSMO (up to 50 mg/ml), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20°C for up to 1 month.
Additional information
SIZE (mg) | 25 MG, 5 MG |
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