Selonsertib, ASK1 inhibitor (TBI4696)
$90.00 – $315.00
ASK1 inhibitor
SKU | Stock | SIZE (mg) | Price | Quantity | ||
---|---|---|---|---|---|---|
TBI4696-5MG | Yes | 5 MG | $90.00 | |||
TBI4696-25MG | Yes | 25 MG | $315.00 |
- Description
- Terms
- Additional information
- Documents
- Reviews (0)
Description
Product Details
Formal Name: 5-(4-Cyclopropylimidazol-1-yl)-2-fluoro-4-methyl-N-[6-(4-propan-2-yl)-1,2,4-triazol-3-yl)pyridine-2-yl]benzamide
Alternate Names: GS-4997
Molecular Formula: C24H24FN7O
Formula Weight: 445.50
CAS Number: 1448428-04-3
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to at least 25 mg/ml)
Storage: -20°C
Stability: ≥ 2 years.
Applications
ASK1 inhibitor
Functions
Potent Apoptosis signal-regulating kinase 1 (ASK1) inhibitor (pIC50 = 8.3) found to improve metabolic parameters in nonalcoholic steatohepatitis, reduce hepatic steatosis, inflammation, and fibrosis. Selonsertib suppressed the efflux function of multidrug resistance (MDR) transporters ABCB1 and ABCG2.
Application Procedures
First dissolved in DMSO (up to at least 25 mg/ml), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20°C for up to 3 months.
Additional information
SIZE (mg) | 25 MG, 5 MG |
---|
Be the first to review “Selonsertib, ASK1 inhibitor (TBI4696)”
You must be logged in to post a review.
Reviews
There are no reviews yet.