STF-62247, Autophagy inducer (TBI1375)
$99.00 – $396.00
Autophagy inducer
SKU | Stock | SIZE (mg) | Price | Quantity | ||
---|---|---|---|---|---|---|
TBI1375-5MG | Yes | 5 MG | $99.00 | |||
TBI1375-25MG | Yes | 25 MG | $396.00 |
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Description
Product Details
Formal Name: N-(3-Methylphenyl)-4-(4-pyridinyl)-2-thiazolamine
Molecular Formula: C15H13N3S
Formula Weight: 477.41
CAS Number: 315702-99-9
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to 25 mg/ml).
Storage: RT
Stability: ≥ 2 years.
Applications
Autophagy inducer
Functions
Specifically induces autophagic cell death in VHL (von Hippel-Lindau)-deficient renal carcinoma cells both in vitro (IC50=625 nM) and in vivo. Renal cell carcinoma cell lines were radiosensitized by induction of autophagy following treatment with STF-62247. Cell permeable
Application Procedures
First dissolved in DMSO (up to 25 mg/ml), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20° for up to 3 months.
Additional information
SIZE (mg) | 25 MG, 5 MG |
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