Smer-28, Autophagy inducer (TBI1287)
$76.00 – $310.00
Autophagy inducer
SKU | Stock | SIZE (mg) | Price | Quantity | ||
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TBI1287-5MG | Yes | 5 MG | $76.00 | |||
TBI1287-25MG | Yes | 25 MG | $310.00 |
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Description
Product Details
Formal Name: 6-Bromo-4-allylaminoquinazoline
Molecular Formula: C11H10BrN3
Formula Weight: 264.12
CAS Number: 307538-42-7
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 2 mg/ml).
Storage: RT
Stability: ≥ 1 year.
Applications
Autophagy inducer
Functions
Induces autophagy via an mTOR-independent pathway. Enhances clearance of β-amyloid protein in cell lines and primary neuronal culture models. May be a useful lead compound for the development of new therapeutics for neurodegenerative diseases. Induces the release of articular cartilage vesicles from healthy articular chondrocytes in a dose- and time-dependent manner. Promotes reprogramming of fibroblasts to neural stem-like cells. Cell permeable..
Application Procedures
First dissolved in DMSO (up to 25 mg/ml) or in Ethanol (up to 2 mg/ml), then diluted to aqueous buffer. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
Additional information
SIZE (mg) | 25 MG, 5 MG |
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