MK-886, 5-Lipoxygenase activating protein (FLAP) inhibitor (TBI1040)
$126.00 – $504.00
5-Lipoxygenase activating protein (FLAP) inhibitor
SKU | Stock | SIZE (mg) | Price | Quantity | ||
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TBI1040-5MG | Yes | 5 MG | $126.00 | |||
TBI1040-25MG | Yes | 25 MG | $504.00 |
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Description
Product Details
Formal Name: 3-[1-(4-chlorobenzyl)-3-t-butyl-thio-5-isopropylindol-2-yl]-2,2-dimethylpropanoic acid
Alternate Names: L-663,536
Molecular Formula: C27H34ClNO2S
Formula Weight: 472.08
CAS Number: 118414-82-7
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to 40 mg/ml).
Storage: RT
Stability: ≥ 1 year.
Applications
5-Lipoxygenase activating protein (FLAP) inhibitor
Functions
Inhibitor of leukotriene biosynthesis(IC50 = 2.5 nM in human PMN) via 5-lipoxygenase-activating protein (FLAP) inhibition (IC50 = 30 nM). Also inhibits PPARα (80% inhibition at 10 µM).
Application Procedures
First dissolved in DMSO (up to 40 mg/ml), then diluted to aqueous buffer. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.
Additional information
SIZE (mg) | 25 MG, 5 MG |
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