BIBW 2992 (Afatinib), EGFR and HER2 inhibitor (TBI4510)
$99.00 – $252.00
EGFR and HER2 inhibitor
SKU | Stock | SIZE (mg) | Price | Quantity | ||
---|---|---|---|---|---|---|
TBI4510-10MG | Yes | 10 MG | $99.00 | |||
TBI4510-50MG | Yes | 50 MG | $252.00 |
- Description
- Terms
- Additional information
- Documents
- Reviews (0)
Description
Product Details
Formal Name: N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4(dimethylamino)-2E-butenamide
Alternate Names: BIBW2992
Molecular Formula: C24H25ClFN5O3
Formula Weight: 485.94
CAS Number: 439081-18-2
Purity: >97%
Formulation: powder
Solubility: Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml).
Storage: -20°C
Stability: ≥ 1 year.
Applications
EGFR and HER2 inhibitor
Functions
Afatinib is a clinically useful kinase inhibitor approved for the treatment of non-small cell lung cancer. It is a potent and highly selective inhibitor of mutant and wild-type EGFR (IC50 = 0.5 nM) and HER2 (IC50 = 14 nM).
Application Procedures
First dissolved in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml), then diluted to aqueous buffer. Solutions in DMSO or Ethanol may be stored at -20°C for up to 2 months.
Additional information
SIZE (mg) | 10 MG, 50 MG |
---|
Be the first to review “BIBW 2992 (Afatinib), EGFR and HER2 inhibitor (TBI4510)”
You must be logged in to post a review.
Reviews
There are no reviews yet.