Mitoguazone 2HCl, Polyamine biosynthesis inhibitor (TBI4552)
$126.00 – $468.00
Polyamine biosynthesis inhibitor
SKU | Stock | SIZE (mg) | Price | Quantity | ||
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TBI4552-10MG | Yes | 10 MG | $126.00 | |||
TBI4552-50MG | Yes | 50 MG | $468.00 |
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Description
Product Details
Formal Name: Methylglyoxal bis(guanylhydrazone) dihydrochloride
Alternate Names: MGBG
Molecular Formula: C5H12N8 · 2HCl
Formula Weight: 257.13
CAS Number: 31959-87-2
Purity: >98%
Formulation: powder
Solubility: Soluble in Water (greater than 25 mg/ml).
Storage: -20°C
Stability: ≥ 1 year.
Applications
Polyamine biosynthesis inhibitor
Functions
Mitoguazone is a potent and reversible inhibitor of S-adenosylmethionine decarboxylase (SAMD or AdoMetDC). SAMD is a component of the polyamine-biosynthetic pathway, thus inhibition may lead to changes in polyamine metabolism. Mitoguazone has also been shown to inhibit diamine oxidase and induce spermidine/spermine N-acetyltransferase. Mitoguazone has been looked at as a potential anti-cancer treatment because of it’s ability to inhibit polyamine synthesis.
Application Procedures
First dissolved in Water (greater than 25 mg/ml), then diluted to aqueous buffer. Solutions in water may be stored at -20°C for up to 1 month.
Additional information
SIZE (mg) | 10 MG, 50 MG |
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