Velpatasvir, Hepatitis C protease inhibitor (TBI4931)
$72.00 – $225.00
Hepatitis C protease inhibitor
SKU | Stock | SIZE (mg) | Price | Quantity | ||
---|---|---|---|---|---|---|
TBI4931-10MG | Yes | 10 MG | $72.00 | |||
TBI4931-50MG | Yes | 50 MG | $225.00 |
- Description
- Terms
- Additional information
- Documents
- Reviews (0)
Description
Product Details
Formal Name: Methyl [(2S)-1-[(2S,5S)-2-[9-[2-[(2S,4S)-1-[(2R)-2-[(methoxycarbonyl)amino]-2-phenylacetyl]-4-(methoxymethyl)pyrrolidin-2-yl]-1H-imidazol-5-yl]-1,11-dihydroisochromeno[4′,3′:6,7]naphtho[1,2-d]imidazol-2-yl]-5-methylpyrrolidin-1-yl]-3-methyl-1-oxobutan-2-yl]carbamate
Alternate Names: GS-5816
Molecular Formula: C49H54N8O8
Formula Weight: 883
CAS Number: 1377049-84-7
Purity: >98%
Formulation: Powder
Solubility: Soluble in DMSO (up to 25 mg/ml)
Storage: -20°C
Stability: ≥ 1 year.
Applications
Hepatitis C protease inhibitor
Functions
Velpatasvir is an extremely potent pan-genotypic hepatitis C virus (HCV) NS5A inhibitor. It is a component of Epclusa® and Vosevi®, two clinically useful medications with 98% and 97%, respectively, cure rates for HCV. It displayed EC50’s for GTs 1-4, 6a ranging from 6-16 pM, GT5a at 75 pM, and GT6e at 130 pM. Velpatasvir also displayed an excellent barrier to viral resistance. It has been shown in silico, that velpatasvir binds to the SARS-CoV-2 spike protein and may be a potential therapeutic.
Application Procedures
First dissolved in DMSO (up to 25 mg/ml), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20°C for up to 3 months.
Additional information
SIZE (mg) | 10 MG, 50 MG |
---|
Be the first to review “Velpatasvir, Hepatitis C protease inhibitor (TBI4931)”
You must be logged in to post a review.
Reviews
There are no reviews yet.