Tyrphostin 9, PDGFRK inhibitor; Oxidative phosphorylation Inhibitor (TBI1535)
$54.00 – $216.00
PDGFRK inhibitor; Oxidative phosphorylation Inhibitor
SKU | Stock | SIZE (mg) | Price | Quantity | ||
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TBI1535-10MG | Yes | 10 MG | $54.00 | |||
TBI1535-50MG | Yes | 50 MG | $216.00 |
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Description
Product Details
Formal Name: 3,5-Di-tert-butyl-4-hydroxybenzylidene-malononitrile
Alternate Names: Tyrphostin a9; Malonoben; AG-17; SF 6847; RG-50872
Molecular Formula: C18H22N2O
Formula Weight: 282.38
CAS Number: 10537-47-0
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 20 mg/ml)
Storage: RT
Stability: ≥ 2 years.
Applications
PDGFRK inhibitor; Oxidative phosphorylation Inhibitor
Functions
Inhibits PDGF receptor tyrosine kinase (IC50 = 1.2 μM) and is a potent (10 nM) inhibitor of oxidative phosphorylation. Inhibits cell growth by disrupting mitochondria. Perturbs the golgi complex and blocks proliferation of vascular smooth muscle cells.
Application Procedures
First dissolved in DMSO (up to 25 mg/ml) or in Ethanol (up to 20 mg/ml), then diluted to aqueous buffer. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
Additional information
SIZE (mg) | 10 MG, 50 MG |
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