Tunicamycin, ER stress inducer (TBI2111)
$135.00 – $540.00
ER stress inducer
SKU | Stock | SIZE (mg) | Price | Quantity | ||
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TBI2111-5MG | Yes | 5 MG | $135.00 | |||
TBI2111-25MG | Yes | 25 MG | $540.00 |
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Description
Product Details
Molecular Formula: C38H62N4O16 (tun. B)
Formula Weight: Avg 840.0
CAS Number: 11089-65-9
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to 40 mg/ml) or in Ethanol (up to 5 mg/ml with warming).
Storage: -20°C
Stability: ≥ 2 years.
Applications
ER stress inducer
Functions
Fermentation product from Streptomyces lysosuperificus. Provided as a mixture of tunicamycin A (C14), B (C15), C (C16) and D (C17) homologs varying in the number of carbon atoms in the fatty acid chain.
Potent inhibitor of GlcNAc phosphotransferase which thereby inhibits glycoprotein biosynthesis. Causes endoplasmic reticulum stress-induced autophagy and unfolded protein response. Arrests cell cycle in late G1.
Application Procedures
First dissolved in DMSO (up to 40 mg/ml) or in Ethanol (up to 5 mg/ml with warming), then diluted to aqueous buffer. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
Additional information
SIZE (mg) | 25 MG, 5 MG |
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