TPCK, Serine protease inhibitor (TBI2290)
$180.00
Serine protease inhibitor
SKU | Stock | SIZE (mg) | Price | Quantity | ||
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TBI2290-500MG | Yes | 500 MG | $180.00 |
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Description
Product Details
Formal Name: N-p-Tosyl-L-phenylalanine chloromethyl ketone
Molecular Formula: C17H18ClNO3S
Formula Weight: 351.80
CAS Number: 402-71-1
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to 10 mg/ml).
Storage: -20°C
Stability: ≥ 1 year.
Applications
Serine protease inhibitor
Functions
TPCK is an irreversible inhibitor of the serine protease chymotrypsin. It also inhibits certain cysteine proteases (bromelain, ficin, papain). TPCK inhibited (IC50 = 5 µM) the mitogen-induced activation of pp70s6k, a mitogen-regulated serine/threonine kinase involved in the G1 to S phase transition of the cell cycle.
Application Procedures
First dissolved in DMSO (up to 10 mg/ml), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20° for up to 3 months.
Additional information
SIZE (mg) | 2 G, 500 MG |
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