THI, S1P lyase inhibitor; Immunomodulator (TBI2477)
$108.00 – $432.00
S1P lyase inhibitor; Immunomodulator
SKU | Stock | SIZE (mg) | Price | Quantity | ||
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TBI2477-5MG | Yes | 5 MG | $108.00 | |||
TBI2477-25MG | Yes | 25 MG | $432.00 |
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Description
Product Details
Formal Name: 2-Acetyl-4-tetrahydroxybutyl Imidazole
Alternate Names: 1-[5-[(1R,2S,3R)-1,2,3,4-tetrahydroxybutyl]-1H-imidazol-2-yl]-ethanone
Molecular Formula: C9H14N2O5
Formula Weight: 230.22
CAS Number: 94944-70-4
Purity: >98%
Formulation: powder
Solubility: Soluble in Water (up to 10 mg/ml).
Storage: -20°C
Stability: ≥ 2 years.
Applications
S1P lyase inhibitor; Immunomodulator
Functions
THI was identified as a biologically active impurity in caramel food coloring. It is a potent inhibitor of sphingosine-1-phosphate (S1P) lyase. It disrupts lymphocyte egress from lymphoid tissue by interfering with S1P gradients. The novel immunomodulatory activity of THI and its biochemical mechanism may represent a new target for the development of new generation of immunosuppressants.
Application Procedures
First dissolved in Water (up to 10 mg/ml), then diluted to aqueous buffer. Solutions in distilled water may be stored at -20°C for up to 3 months.
Additional information
SIZE (mg) | 25 MG, 5 MG |
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