Synaptamide, Endogenous agonist at GPR110 (TBI1194)
$54.00 – $225.00
Endogenous agonist at GPR110
SKU | Stock | SIZE (mg) | Price | Quantity | ||
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TBI1194-5MG | Yes | 5 MG | $54.00 | |||
TBI1194-25MG | Yes | 25 MG | $225.00 |
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Description
Product Details
Formal Name: N-Docosahexaenoylethanolamide
Alternate Names: DHA-ethanolamide
Molecular Formula: C24H37NO2
Formula Weight: 371.56
CAS Number: 162758-94-3
Purity: >98%
Formulation: Oil
Solubility: Soluble in DMSO (up to 35 mg/ml).
Storage: -80°C
Stability: ≥ 1 year.
Applications
Endogenous agonist at GPR110
Functions
Anandamide-like lipid mediator produced from DHA in the brain. Stimulates neurite growth, synaptogenesis and glutamatergic synaptic activity in developing hippocampal neurons at 10-100 nM. Potently induces neuronal differentiation of neural stem cells. Promotes growth of cortical axons vial modulation of hedgehog signaling. Binds to and activates orphan receptor GPR110, stimulating cAMP production at low nM concentrations. Reduces LPS-induced TNFα production in cultured microglia cells and ameliorates LPS-induced neuroinflammation in a mouse model.
Application Procedures
First dissolved in DMSO (up to 35 mg/ml), then diluted to aqueous buffer. Solutions in DMSO may be stored under inert gas at -80°C for up to 3 months.
Additional information
SIZE (mg) | 25 MG, 5 MG |
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