SL-01, p53/mdm2 inhibitor (TBI1326)
$54.00 – $144.00
p53/mdm2 inhibitor
SKU | Stock | SIZE (mg) | Price | Quantity | ||
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TBI1326-50MG | Yes | 50 MG | $54.00 | |||
TBI1326-250MG | Yes | 250 MG | $144.00 |
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Description
Product Details
Formal Name: N-Benzyloxycarbonyl-L-phenylalaninylchloromethylketone
Alternate Names: ZPCK
Molecular Formula: C18H18ClNO3
Formula Weight: 331.80
CAS Number: 26049-94-5
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to 50 mg/ml) or in Ethanol (up to 15 mg/ml with warming).
Storage: -20°C
Stability: ≥ 2 years.
Applications
p53/mdm2 inhibitor
Functions
Inhibits the p53-MDM2 interaction (20 μM). Alkylates one catalytic histidine residue (His-397) participating in the charge-relay system of carboxypeptidase Y. Has also been shown to inhibit bovine chymotrypsin A-γ. A potent inhibitor of the severe acute respiratory syndrome coronavirus (SARS-CoV) main protease (Mpro), Ki=306 nM.
Application Procedures
First dissolved in DMSO (up to 50 mg/ml) or in Ethanol (up to 15 mg/ml with warming), then diluted to aqueous buffer. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.
Additional information
SIZE (mg) | 250 MG, 50 MG |
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