Sivelestat, Leukocyte elastase inhibitor (TBI1102)
$97.00 – $396.00
Leukocyte elastase inhibitor
SKU | Stock | SIZE (mg) | Price | Quantity | ||
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TBI1102-5MG | Yes | 5 MG | $97.00 | |||
TBI1102-25MG | Yes | 25 MG | $396.00 |
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Description
Product Details
Formal Name: N-{2-[({4-[(2,2-Dimethylpropanoyl)oxy]phenyl}sulfonyl)amino]benzoyl}glycine sodium
Alternate Names: ONO-5046
Molecular Formula: C20H21N2O7
Formula Weight: 456.45
CAS Number: 127373-66-4
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to 20 mg/ml).
Storage: RT
Stability: ≥ 1 year.
Applications
Leukocyte elastase inhibitor
Functions
Potent and selective leukocyte elastase inhibitor, IC50 = 44 nM. Displays no activity at a variety of other proteases. Inhibits NF-κB activation and LTB4-induced neutrophil migration in vitro. Significantly attenuates ischemia-induced spinal cord injury, decreases serum cytokine levels and reduces acute inflammatory lung injury in vivo.
Application Procedures
First dissolved in DMSO (up to 20 mg/ml), then diluted to aqueous buffer.
Additional information
SIZE (mg) | 25 MG, 5 MG |
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