RVX-208, BET bromodomain inhibitor (TBI1487)
$122.00 – $490.00
BET bromodomain inhibitor
SKU | Stock | SIZE (mg) | Price | Quantity | ||
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TBI1487-5MG | Yes | 5 MG | $122.00 | |||
TBI1487-25MG | Yes | 25 MG | $490.00 |
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Description
Product Details
Formal Name: 2-[4-(2-hydroxyethoxy)-3,5-dimethylphenyl]-5,7-dimethoxy-4(3H)-quinzolinone
Molecular Formula: C20H22N2O5
Formula Weight: 370.41
CAS Number: 1044870-39-4
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to 75 mg/ml) or in Ethanol (up to 4 mg/ml).
Storage: -20°C
Stability: ≥ 2 years.
Applications
BET bromodomain inhibitor
Functions
RVX-208 is a potent BET bromodomain antagonist with IC50 of 0.510 μM for BD2, with approximately 170-fold selectivity over BD1. Increases apolipoprotein A-1 and HDL cholesterol in vitro and in vivo. Reduces atherosclerosis.
Application Procedures
First dissolved in DMSO (up to 75 mg/ml) or in Ethanol (up to 4 mg/ml), then diluted to aqueous buffer. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.
Additional information
SIZE (mg) | 25 MG, 5 MG |
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