RSL3, GPX4 Inhibitor / Ferroptosis inducer (TBI3417)
$153.00 – $450.00
GPX4 Inhibitor / Ferroptosis inducer
SKU | Stock | SIZE (mg) | Price | Quantity | ||
---|---|---|---|---|---|---|
TBI3417-5MG | Yes | 5 MG | $153.00 | |||
TBI3417-25MG | Yes | 25 MG | $450.00 |
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Description
Product Details
Formal Name: (1S,3R)-Methyl 2-(2-chloroacetyl)-2,3,4,9-tetrahydro-1-[4-(methoxycarbonyl)phenyl]-1H-pyrido[3,4-b]indole-3-carboxylate
Alternate Names: 1S,3R-RSL3
Molecular Formula: C23H21ClN2O5
Formula Weight: 440.90
CAS Number: 1219810-16-8
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to 45 mg/ml)
Storage: -20°C
Stability: ≥ 2 years.
Applications
GPX4 Inhibitor / Ferroptosis inducer
Functions
Inhibits glutathione peroxidase (GPX4) inducing ferroptosis. Effectively induces ferroptosis in glioblastoma cells. Everolimus in combination with RSL3 synergistically inhibits the viability of renal cell carcinoma (RCC) cells suggesting a mechanism by which RCC drug resistance may be overcome.
Application Procedures
First dissolved in DMSO (up to 45 mg/ml), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20°C for up to 1 month.
Additional information
SIZE (mg) | 25 MG, 5 MG |
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