Roxatidine, Histamine H2 antagonist, antiulcer, anti-inflammatory (TBI5046)
$162.00 – $648.00
Histamine H2 antagonist, antiulcer, anti-inflammatory
SKU | Stock | SIZE (mg) | Price | Quantity | ||
---|---|---|---|---|---|---|
TBI5046-5MG | Yes | 5 MG | $162.00 | |||
TBI5046-25MG | Yes | 25 MG | $648.00 |
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Description
Product Details
Formal Name: 2-hydroxy-N-(3-(3-(piperidin-1-ylmethyl)phenoxy)propyl)acetamide
Molecular Formula: C17H26N2O3
Formula Weight: 306.40
CAS Number: 78273-80-0
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to 25 mg/ml)
Storage: -20°C
Stability: ≥ 2 years.
Applications
Histamine H2 antagonist, antiulcer, anti-inflammatory
Functions
A novel histamine H2 receptor antagonist. Suppresses inflammatory responses via inhibition of NFκB and p38 MAPK activation in LPS-induced RAW 264.7 macrophages. Clinically useful agent for prevention and healing of gastric and duodenal ulcers and bleeding. Attenuates degradation of extracellular matrix in osteoarthritis models by inactivating the NFκB pathway.
Application Procedures
First dissolved in DMSO (up to 25 mg/ml), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20° for up to 3 months.
Additional information
SIZE (mg) | 25 MG, 5 MG |
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