PJ-34 HCl, PARP1,2 inhibitor (TBI2395)
$101.00 – $245.00
PARP1,2 inhibitor
SKU | Stock | SIZE (mg) | Price | Quantity | ||
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TBI2395-5MG | Yes | 5 MG | $101.00 | |||
TBI2395-25MG | Yes | 25 MG | $245.00 |
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Description
Product Details
Formal Name: N-(6-Oxo-5,6-dihydrophenanthridin-2-yl)-(N,N-dimethylamino)acetamide hydrochloride
Molecular Formula: C17H17N3O2
Formula Weight: 331.81
CAS Number: 344458-15-7
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to 30 mg/ml) or in Water (up to 20 mg/ml).
Storage: RT
Stability: ≥ 2 years.
Applications
PARP1,2 inhibitor
Functions
A potent and selective inhibitor of PARP1 and 2. EC50 = 20 nM. Reduces ischemia reperfusion injury in a mouse model. Displays anti-inflammatory effects in a transient focal cerebral ischemia mouse model. Causes PARP1 independent, p21 dependent mitotic arrest.
Application Procedures
First dissolved in DMSO (up to 30 mg/ml) or in Water (up to 20 mg/ml), then diluted to aqueous buffer. Solutions in DMSO or distilled water may be stored at -20° for up to 3 months.
Additional information
SIZE (mg) | 25 MG, 5 MG |
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