Pifithrin mu, Hsp70 inhibitor (TBI1180)
$81.00 – $306.00
Hsp70 inhibitor
SKU | Stock | SIZE (mg) | Price | Quantity | ||
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TBI1180-5MG | Yes | 5 MG | $81.00 | |||
TBI1180-25MG | Yes | 25 MG | $306.00 |
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Description
Product Details
Formal Name: 2-Phenylethynesulfonamide
Alternate Names: PES; NSC-303580
Molecular Formula: C8H7NO2S
Formula Weight: 181.21
CAS Number: 64984-31-2
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to 20 mg/ml) or in Ethanol (up to 20 mg/ml).
Storage: -20°C
Stability: ≥ 2 years.
Applications
Hsp70 inhibitor
Functions
Selectively interacts with HSP70 and disrupts its association with co-chaperones and substrate proteins. Inhibits p53 binding to antiapoptotic proteins Bcl-xL and Bcl-2. Recues primary mouse thymocytes from P53-mediated apoptosis induced by radiation. Cell permeable.
Application Procedures
First dissolved in DMSO (up to 20 mg/ml) or in Ethanol (up to 20 mg/ml), then diluted to aqueous buffer. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
Additional information
SIZE (mg) | 25 MG, 5 MG |
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