Pifithrin α, p53 inhibitor (TBI2480)
$90.00 – $351.00
p53 activator
SKU | Stock | SIZE (mg) | Price | Quantity | ||
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TBI2480-5MG | Yes | 5 MG | $90.00 | |||
TBI2480-25MG | Yes | 25 MG | $351.00 |
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Description
Product Details
Formal Name: 1-(4-Methylphenyl)-2-(4,5,6,7-tetrahydro-2-imino-3(2H)-benzothiazolyl)ethanone · HBr
Alternate Names: PFT-α
Molecular Formula: C16H18N2OS · HBr
Formula Weight: 367.31
CAS Number: 63208-82-2
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to 25 mg/ml).
Storage: -20°C
Stability: ≥ 1 year.
Applications
p53 inhibitor
Functions
Pifithrin α (63208-82-2) is a reversible inhibitor of p53-mediated transcription and p53-dependent apoptosis. Enhances survival after genotoxic stress and protects against chemotherapeutic side-effects in mice. Supresses self-renewal of embryonic stem cells. Pfithrin α protects against neuronal death in models of stroke and neurodegenerative disease. AhR agonist.
Application Procedures
First dissolved in DMSO (up to 25 mg/ml), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20°C for up to 3 months.
Additional information
SIZE (mg) | 25 MG, 5 MG |
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