PD-98059, MEK inhibitor (TBI2159)
$81.00 – $288.00
MEK inhibitor
SKU | Stock | SIZE (mg) | Price | Quantity | ||
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TBI2159-5MG | Yes | 5 MG | $81.00 | |||
TBI2159-25MG | Yes | 25 MG | $288.00 |
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Description
Product Details
Formal Name: 2-(2-Amino-3-methoxyphenyl)-4H-1-benzopyran-4-one
Alternate Names: 2’-Amino-3’-methoxyflavone
Molecular Formula: C16H13NO3
Formula Weight: 267.29
CAS Number: 167869-21-8
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to 6 mg/ml)
Storage: RT
Stability: ≥ 1 year.
Applications
MEK inhibitor
Functions
Inhibitor of mitogen-activated protein kinase kinase (MKK / MEK). Acts via binding to the inactivated form of MEK, preventing its phosphorylation by cRAF or MEK kinase (IC50=2-7μM). Accelerates differentiation of RAW264.7 cells into osteoclast-like cells. Mimics BMP4 in supporting self renewal of embryonic stem cells.
Application Procedures
First dissolved in DMSO (up to 6 mg/ml), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20° for up to 3 months.
Additional information
SIZE (mg) | 25 MG, 5 MG |
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