P5091, DUB USP7 inhibitor (TBI1422)
$108.00 – $432.00
DUB USP7 inhibitor
SKU | Stock | SIZE (mg) | Price | Quantity | ||
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TBI1422-5MG | Yes | 5 MG | $108.00 | |||
TBI1422-25MG | Yes | 25 MG | $432.00 |
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Description
Product Details
Formal Name: 1-[5-[(2,3-Dichlorophenyl)thio]-4-nitro-2-thienyl]ethanone
Molecular Formula: C12H7Cl2NO3S2
Formula Weight: 348.23
CAS Number: 882257-11-6
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to 20 mg/ml) or in Ethanol (up to 40 mg/ml with warming).
Storage: RT
Stability: ≥ 1 year.
Applications
DUB USP7 inhibitor
Functions
Selective inhibitor of the ubiquitin-specific protease USP7 ( IC50=4.2 μM). Induces apoptosis in multiple myeloma cells and overcomes bortezomib resistance. Displays antiangiogenic activity in vivo. Cell permeable
Application Procedures
First dissolved in DMSO (up to 20 mg/ml) or in Ethanol (up to 40 mg/ml with warming), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20° for up to 3 months.
Additional information
SIZE (mg) | 25 MG, 5 MG |
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