ML335, TREK-1,2 activator (TBI3648)
$99.00 – $396.00
TREK-1,2 activator
SKU | Stock | SIZE (mg) | Price | Quantity | ||
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TBI3648-5MG | Yes | 5 MG | $99.00 | |||
TBI3648-25MG | Yes | 25 MG | $396.00 |
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Description
Product Details
Formal Name: N-(2,4-Dichlorobenzyl)-4-(methylsulfonamido)benzamide
Molecular Formula: C15H14Cl2N2O3S
Formula Weight: 373.25
CAS Number: 825658-06-8
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to 50 mg/ml) or in Ethanol (up to 20 mg/ml with warming)
Storage: -20°C
Stability: ≥ 2 years.
Applications
TREK-1,2 activator
Functions
Two-pore domain potassium (K2P) channels of the TREK subfamily regulate neuronal excitability, influence pain, temperature perception and responses to anaesthetics. ML335 is a novel, selective TREK-1,2 activator with EC50s of 14.3 and 5.2 μM. It represents an important new pharmacological tool for studying the physiology of TREK channels.
Application Procedures
First dissolved in DMSO (up to 50 mg/ml) or in Ethanol (up to 20 mg/ml with warming), then diluted to aqueous buffer. Solutions in DMSO or ethanol may be stored at -20° for up to 2 months.
Additional information
SIZE (mg) | 25 MG, 5 MG |
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