ML-167, Clk4 inhibitor (TBI4543)
$135.00 – $531.00
Clk4 inhibitor
SKU | Stock | SIZE (mg) | Price | Quantity | ||
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TBI4543-5MG | Yes | 5 MG | $135.00 | |||
TBI4543-25MG | Yes | 25 MG | $531.00 |
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Description
Product Details
Formal Name: [5-[4-[(5-Methylfuran-2-yl)methylamino]quinazolin-6-yl]furan-2-yl]methanol
Alternate Names: CID 44968231
Molecular Formula: C19H17N2O3
Formula Weight: 335.36
CAS Number: 1285702-20-6
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (greater than 25 mg/ml).
Storage: -20°C
Stability: ≥ 1 year.
Applications
Clk4 inhibitor
Functions
ML167 is a highly selective cell permeable inhibitor of Cdc2-like kinase 4 (Clk4) – IC50 = 136nM. It displays at least 10-fold greater selectivity over the related kinases Clk1(1.52 µM), Clk2(1.65µM), Clk3(>10µM), Dyrk1A(>10µM), and Dyrk1B(4.4 µM).
Application Procedures
First dissolved in DMSO (greater than 25 mg/ml), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20° for up to 3 months.
Additional information
SIZE (mg) | 25 MG, 5 MG |
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