MK-571, Leukotriene Cys LT1 antagonist (TBI1039)

Description

Product Details

Formal Name: 5-(3-(2-(7-Chloroquinolin-2-yl)ethenyl)phenyl)-8-dimethylcarbamyl-4,6-dithiaoctanoic acid, sodium salt

Alternate Names: L-660711

Molecular Formula: C₂₆H₂₆ClN₂O₃S₂ · Na

Formula Weight: 537.10

CAS Number: 115104-28-4

Purity: >98%

Formulation: powder

Solubility: Soluble in DMSO (up to 50 mg/ml).

Storage: RT

Stability: ≥ 1 year.

 

Applications

Leukotriene Cys LT1 antagonist

 

Functions

Potent (EC50 = 1.3nM) and selective Leukotriene D4 antagonist(LTD4) displaying inverse agonist activity, Blocks binding of LTD4 to human (Ki = 0.22 nM) and guinea pig (Ki = 2.1 nM) lung membranes.  Selective for the CysLT1 receptor.   Multidrug resistance protein 1 (MRP1) inhibitor.

 

Application Procedures

First dissolved in DMSO (up to 50 mg/ml), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20°C for up to 2 months.

Additional information

SIZE (mg)	25 MG, 5 MG

Datasheet:

TBI1039_MK-571

MSDS:

TBI1039_MK-571_MSDS_2024