Lovastatin, HMG-CoA reductase inhibitor (TBI1222)
$90.00 – $297.00
HMG-CoA reductase inhibitor
SKU | Stock | SIZE (mg) | Price | Quantity | ||
---|---|---|---|---|---|---|
TBI1222-100MG | Yes | 100 MG | $90.00 | |||
TBI1222-500MG | Yes | 500 MG | $297.00 |
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Description
Product Details
Formal Name: 2-Methyl-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-[2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl]-1-naphthalenyl
ester butanoic acid
Alternate Names: Mevinolin
Molecular Formula: C24H36O5
Formula Weight: 404.55
CAS Number: 75330-75-3
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml).
Storage: -20°C
Stability: ≥ 1 year.
Applications
HMG-CoA reductase inhibitor
Functions
Blocks cholesterol and isoprenoid biosynthesis via inhibition of HMG-CoA reductase (Ki=1nM for acid form). Induces apoptosis in various cell lines. Causes cell cycle arrest in early G1 phase. Clinically useful antihyperlipemic agent. Cell permeable.
Application Procedures
First dissolved in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml), then diluted to aqueous buffer. Solutions in DMSO or Ethanol may be stored at -20°C for up to 2 months.
Additional information
SIZE (mg) | 500 MG, 100 MG |
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