LDN-57444, DUB inhibitor (TBI1303)
$108.00 – $360.00
DUB inhibitor
SKU | Stock | SIZE (mg) | Price | Quantity | ||
---|---|---|---|---|---|---|
TBI1303-5MG | Yes | 5 MG | $108.00 | |||
TBI1303-25MG | Yes | 25 MG | $360.00 |
- Description
- Terms
- Additional information
- Documents
- Reviews (0)
Description
Product Details
Formal Name: 5-Chloro-1-[(2,5-dichlorophenyl)methyl]-1H-indole-2,3-dione 3-(O-acetyloxime)
Molecular Formula: C17H11Cl3N2O3
Formula Weight: 397.65
CAS Number: 668467-91-2
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to 20 mg/ml).
Storage: -20°C
Stability: ≥ 2 years.
Applications
DUB inhibitor
Functions
Inhibits ubiquitin C-terminal hydrolase (UCH-L1) (Ki=0.4 μM). Decreases proteasome activity and increases levels of ubiquitinated proteins. Induces apoptosis. Causes dramatic alterations in synaptic protein distribution and spine morphology in vivo. Cell permeable.
Application Procedures
First dissolved in DMSO (up to 20 mg/ml), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20° for up to 1 week.
Additional information
SIZE (mg) | 25 MG, 5 MG |
---|
Be the first to review “LDN-57444, DUB inhibitor (TBI1303)”
You must be logged in to post a review.
Reviews
There are no reviews yet.