Ivabradine HCl, Cardiac ion channel blocker (TBI2694)
$108.00 – $396.00
Cardiac ion channel blocker
SKU | Stock | SIZE (mg) | Price | Quantity | ||
---|---|---|---|---|---|---|
TBI2694-10MG | Yes | 10 MG | $108.00 | |||
TBI2694-50MG | Yes | 50 MG | $396.00 |
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Description
Product Details
Formal Name: 3-[3-[[(7S)-3,4-Dimethoxy-7-bicyclo[4.2.0]octa-1,3,5-trienyl]methyl-methylamino]propyl]7,8-dimethoxy-2,5-dihydro-1H-3-benzazepin-4-one hydrochloride
Molecular Formula: C27H36N2O5·HCl
Formula Weight: 505.05
CAS Number: 148849-67-6
Purity: >98%
Formulation: Powder
Solubility: Soluble in DMSO (up to 20 mg/ml)
Storage: -20°C
Stability: ≥ 1 year.
Applications
Cardiac ion channel blocker
Functions
Ivabradine (148849-67-6) is a clinically useful heart failure and chronic unstable angina medication. It lowers heart rate via inhibition of hyperpolarization-activated cyclic nucleotide-gated channels (HCN) expressed in the sinoatrial node (IC50’s: HCN1 = 2.05 µM, HCN2 = 2.29 µM, HCN3 = 2.51 µM, HCN4 = 2.15 µM).
Application Procedures
First dissolved in DMSO (up to 20 mg/ml), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20°C for up to 1 month.
Additional information
SIZE (mg) | 10 MG, 50 MG |
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