Imiquimod, TLR7 Agonist (TBI4230)
$54.00 – $135.00
TLR7 Agonist
SKU | Stock | SIZE (mg) | Price | Quantity | ||
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TBI4230-50MG | Yes | 50 MG | $54.00 | |||
TBI4230-250MG | Yes | 250 MG | $135.00 |
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Description
Product Details
Formal Name: 1-(2-Methylpropyl)imidazo[4,5-c]quinolin-4-amine
Alternate Names: R837
Molecular Formula: C14H14N4
Formula Weight: 240.30
CAS Number: 99011-02-6
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to 2 mg/ml with warming)
Storage: -20°C
Stability: ≥ 1 year.
Applications
TLR7 Agonist
Functions
Imiquimod is a Toll-like receptor 7/8 agonist with anti-viral and anti-tumor properties. Enhances innate immune system leading to Th1-mediated antitumor immune response. Increases levels of IFNa, TNFa, and IL-12. Imiquimod has also been shown to act as an antagonist at adenosine A1 and A2A receptors augmenting its proinflammatory effects. Clinically useful for the treatment of basal cell carcinoma, actinic keratosis, and genital warts. Imiquimod also upregulates the expression of opioid growth factor receptor(OGFr). OGF is involved in regulation of inhibitory kinases in the cell cycle process.
Application Procedures
First dissolved in DMSO (up to 2 mg/ml with warming), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20°C for up to 3 months.
Additional information
SIZE (mg) | 250 MG, 50 MG |
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