Gue-1654, OXE-R antagonist (TBI1425)
$108.00 – $432.00
OXE-R antagonist
SKU | Stock | SIZE (mg) | Price | Quantity | ||
---|---|---|---|---|---|---|
TBI1425-5MG | Yes | 5 MG | $108.00 | |||
TBI1425-25MG | Yes | 25 MG | $432.00 |
- Description
- Terms
- Additional information
- Documents
- Reviews (0)
Description
Product Details
Formal Name: N-[7-(Methylthio)benzo[1,2-d:4,3-d’]bisthiazol-2-yl]-α-phenylbenzeneacetamide
Molecular Formula: C23H17N3OS3
Formula Weight: 447.59
CAS Number: 397290-30-1
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (40 mg/ml)
Storage: -20°C
Stability: ≥ 1 year.
Applications
OXE-R antagonist
Functions
Gue1654 is a biased antagonist for the oxoeicosanoid receptor 1 (OXE-R, GPR170)1, the receptor for 5-Oxo-ETE, a proinflammatory eicosanoid. It selectively inhibits Gβγ but not Gαi signaling upon activation of the Gαi-βγ heterotrimer by OXE-R. Gue1654 alleviated coronary artery ligation-induced ischemic myocardial injury in a mouse model.
Application Procedures
First dissolved in DMSO (40 mg/ml), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20°C for up to 3 months.
Additional information
SIZE (mg) | 25 MG, 5 MG |
---|
Be the first to review “Gue-1654, OXE-R antagonist (TBI1425)”
You must be logged in to post a review.
Reviews
There are no reviews yet.