GSK2982772, Highly selective RIPK1 inhibitor (TBI4792)
$171.00 – $630.00
Highly selective RIPK1 inhibitor
SKU | Stock | SIZE (mg) | Price | Quantity | ||
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TBI4792-5MG | Yes | 5 MG | $171.00 | |||
TBI4792-25MG | Yes | 25 MG | $630.00 |
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Description
Product Details
Formal Name: (S)-5-Benzyl-N-(5-methyl-4-oxo-2,3,4,5-tetrahydrobenzo[b]-[1,4]oxazepin-3-yl)-4H-1,2,4-traizole-3-carboxamide
Molecular Formula: C20H19N5O3
Formula Weight: 377.40
CAS Number: 1622848-92-3
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to 25 mg/ml)
Storage: -20°C
Stability: ≥ 2 years.
Applications
Highly selective RIPK1 inhibitor
Functions
GSK2982772 is a highly selective inhibitor of Receptor-interacting Protein 1 kinase (RIP1); IC50 = 1.6 nM. Novel anti-inflammatory agent previously in clinical trials for psoriasis, rheumatoid arthritis, and ulcerative colitis.
Application Procedures
First dissolved in DMSO (up to 25 mg/ml), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20°C for up to 1 month.
Additional information
SIZE (mg) | 25 MG, 5 MG |
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