FK-866 HCl, NAD biosynthesis inhibitor (TBI1109)
$126.00 – $504.00
NAD biosynthesis inhibitor
SKU | Stock | SIZE (mg) | Price | Quantity | ||
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TBI1109-5MG | Yes | 5 MG | $126.00 | |||
TBI1109-25MG | Yes | 25 MG | $504.00 |
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Description
Product Details
Molecular Formula: C24H29N3O2 ∙ HCl
Formula Weight: 428.00
CAS Number: 658084-64-1
Purity: >98%
Formulation: powder
Solubility: Soluble in Water (up to 40 mg/ml).
Storage: -20°C (hygroscopic)
Stability: ≥ 2 years.
Applications
NAD biosynthesis inhibitor
Functions
A highly specific, noncompetitive inhibitor of nicotinamide phosphoribosyltransferase inhibitor (Ki=0.4 nM). Induces tumor cell apoptosis via gradual intracellular depletion of NAD+. Extends lifespan of human cells mediated by activation of the longevity enzyme SIRT1. Suppresses colorectal cancer cell growth and sensitizes pancreatic adenocarcinoma cells to death by other agents. Cell permeable.
Application Procedures
First dissolved in Water (up to 40 mg/ml), then diluted to aqueous buffer. Solutions in distilled water may be stored at -20°C for up to 2 months.
Additional information
SIZE (mg) | 25 MG, 5 MG |
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