Epalrestat, Aldose reductase inhibitor (TBI4423)
$90.00 – $288.00
Aldose reductase inhibitor
| SKU | Stock | SIZE (mg) | Price | Quantity | ||
|---|---|---|---|---|---|---|
| TBI4423-5MG | Yes | 5 MG | $90.00 | |||
| TBI4423-25MG | Yes | 25 MG | $288.00 |
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Description
Product Details
Formal Name: 2-[(5Z)-5-[(E)-3-phenyl-2-methylprop-2-enylidene]- 4-oxo-2-thioxo-3-thiazolidinyl]acetic acid
Alternate Names: ONO-2235
Molecular Formula: C15H13NO3S2
Formula Weight: 319.40
CAS Number: 82159-09-9
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to 5 mg/ml).
Storage: -20°C
Stability: ≥ 1 year.
Applications
Aldose reductase inhibitor
Functions
Epalrestat is an aldose reductase inhibitor (IC50 = 10 nM (rat lens) and 25 nM (human placenta). It reduces sorbitol accumulation in the sciatic nerve, erythrocytes and ocular tissue. May be used to prevent or slow the progression of diabetic neuropathy.
Application Procedures
First dissolved in DMSO (up to 5 mg/ml), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20° for up to 2 months.
Additional information
| SIZE (mg) | 25 MG, 5 MG |
|---|
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