DJ-V 159, GPRC6A agonist; Stimulates insulin secretion in beta cells (TBI3582)
$90.00 – $360.00
GPRC6A agonist; Stimulates insulin secretion in beta cells
| SKU | Stock | SIZE (mg) | Price | Quantity | ||
|---|---|---|---|---|---|---|
| TBI3582-5MG | Yes | 5 MG | $90.00 | |||
| TBI3582-25MG | Yes | 25 MG | $360.00 |
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Description
Product Details
Formal Name: N1,N3-Bis(4-cyano-3-(trifluoromethyl)phenyl)isophthalamide
Molecular Formula: C24H12F6N4O2
Formula Weight: 502.40
CAS Number: 2253744-53-3
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to 60 mg/ml)
Storage: RT
Stability: ≥ 2 years.
Applications
GPRC6A agonist; Stimulates insulin secretion in beta cells
Functions
GPRC6A is the receptor for osteocalcin as well as structurally unrelated ligands including L-amino acids, cations and anabolic steroids. GPRC6A is a potential therapeutic target for treating type 2 diabetes. DJ-V 159 is an agonist at GPRC6A which activates ERK and upregulates cAMP levels in HEK-193 cells expressing GPRC6A. It stimulates insulin secretion in mouse β-cells and lowers blood glucose in mouse models.
Application Procedures
First dissolved in DMSO (up to 60 mg/ml), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20° for up to 3 months.
Additional information
| SIZE (mg) | 25 MG, 5 MG |
|---|
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