Dasatinib, Src and Bcr/Abl inhibitor (TBI2126)
$90.00 – $171.00
Src and Bcr/Abl inhibitor
SKU | Stock | SIZE (mg) | Price | Quantity | ||
---|---|---|---|---|---|---|
TBI2126-5MG | Yes | 5 MG | $90.00 | |||
TBI2126-25MG | Yes | 25 MG | $171.00 |
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Description
Product Details
Formal Name: N-(2-chloro-6-methylphenyl)-2-(6-(4-(2-hydroxyethyl)-piperazin-1-yl)-2-methylpyrimidin-4-ylamino) thiazole-5-carboxamide
Alternate Names: BMS-354825
Molecular Formula: C22H26ClN7O2S
Formula Weight: 488.00
CAS Number: 302962-49-8
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to 200 mg/ml).
Storage: -20°C
Stability: ≥ 1 year.
Applications
Src and Bcr/Abl inhibitor
Functions
Inhibits Src, Bcr/Abl and Lyn tyrosine kinases (IC50= 0.55, 3.0 and 8.5 nM respectively). Suppresses invasion and induces cell cycle arrest and apoptosis of head and neck squamous cell carcinoma and non-small cell lung cancer cells.
Application Procedures
First dissolved in DMSO (up to 200 mg/ml), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20° for up to 2 months.
Additional information
SIZE (mg) | 25 MG, 5 MG |
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