Daminozide, KDM2/7 demethylase inhibitor (TBI1403)
$72.00 – $162.00
KDM2/7 demethylase inhibitor
SKU | Stock | SIZE (mg) | Price | Quantity | ||
---|---|---|---|---|---|---|
TBI1403-50MG | Yes | 50 MG | $72.00 | |||
TBI1403-250MG | Yes | 250 MG | $162.00 |
- Description
- Terms
- Additional information
- Documents
- Reviews (0)
Description
Product Details
Formal Name: 1-(2,2-Dimethylhydrazide)butanedioic acid
Alternate Names: N-(Dimethylamino)succinamic acid
Molecular Formula: C6H12N2O3
Formula Weight: 160.17
CAS Number: 1596-84-5
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to 50 mg/ml), or in Water (up to 20 mg/ml with warming).
Storage: RT
Stability: ≥ 2 years.
Applications
KDM2/7 demethylase inhibitor
Functions
A selective inhibitor of the KDM2/7 JmjC subfamily of histone demethylases. IC50=1.5, 0.55 and 2.1 μM for KDM2A, PHF8 and KDM7A respectively. Highly selective over other subfamily members (KDM3, KDM4, KDM5 and KDM6) as well as other 2-oxoglutarate oxygenases (FIH, PHD2 and BBOX1), IC50>100 μM1.
Application Procedures
First dissolved in DMSO (up to 50 mg/ml), or in Water (up to 20 mg/ml with warming), then diluted to aqueous buffer. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
Additional information
SIZE (mg) | 250 MG, 50 MG |
---|
Be the first to review “Daminozide, KDM2/7 demethylase inhibitor (TBI1403)”
You must be logged in to post a review.
Reviews
There are no reviews yet.