CK-666, ARP2/3 inhibitor (TBI3346)
$117.00 – $432.00
ARP2/3 inhibitor
SKU | Stock | SIZE (mg) | Price | Quantity | ||
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TBI3346-5MG | Yes | 5 MG | $117.00 | |||
TBI3346-25MG | Yes | 25 MG | $432.00 |
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Description
Product Details
Formal Name: 2-Fluoro-N-[2-methyl-1H-indol-3-yl)ethyl]benzamide
Molecular Formula: C18H17FN2O
Formula Weight: 296.34
CAS Number: 442633-00-3
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to 45 mg/ml) or in Ethanol (up to 30 mg/ml).
Storage: -20°C
Stability: ≥ 1 year.
Applications
ARP2/3 inhibitor
Functions
A potent, selective and reversible inhibitor of ARP2/3 complex (actin related proteins 2 and 3) with an IC50 = 4 µM for human ARP2/3. Blocks actin nucleation and radically alters lamellipodial actin architecture, suspended cell shape and the cell spreading process. CK-666 attenuates BBB dysfunction induced by methamphetamine. It is an important new tool for studying actin assembly and the diverse range of actin-related processes in normal and pathophysiology.
Application Procedures
First dissolved in DMSO (up to 45 mg/ml) or in Ethanol (up to 30 mg/ml), then diluted to aqueous buffer. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
Additional information
SIZE (mg) | 25 MG, 5 MG |
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