CHIR-99021, GSK-3β inhibitor (TBI1279)
$108.00 – $306.00
GSK-3β inhibitor
SKU | Stock | SIZE (mg) | Price | Quantity | ||
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TBI1279-5MG | Yes | 5 MG | $108.00 | |||
TBI1279-25MG | Yes | 25 MG | $306.00 |
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Description
Product Details
Formal Name: 6-[[2-[[4-(2,4-Dichlorophenyl)-5-(5-methyl-1H-imidazol-2-yl)-2-pyrimidinyl]amino]ethyl]amino]-3-pyridinecarbonitrile
Molecular Formula: C22H18Cl2N8
Formula Weight: 465.35
CAS Number: 252917-06-9
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to 25 mg/ml).
Storage: -20°C
Stability: ≥ 2 years.
Applications
GSK-3β inhibitor
Functions
Potent and selective inhibitor of glycogen synthase kinase-3β (GSK3β, IC50 = 5 nM) and GSK3α (IC50 = 10 nM). Induces osteoblastogenesis, increases mineralization and inhibits adipogenesis in ST2 cells. Promotes replication and survival of pancreatic beta cells. Enhances differentiation and reduces proliferation of adult human olfactory epithelium neural precursors. Cell permeable and active in vivo.
Application Procedures
First dissolved in DMSO (up to 25 mg/ml), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20° for up to 3 months.
Additional information
SIZE (mg) | 25 MG, 5 MG |
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