Cerulenin, Fatty acid biosynthesis inhibitor (TBI2062)
$216.00 – $864.00
Fatty acid biosynthesis inhibitor
SKU | Stock | SIZE (mg) | Price | Quantity | ||
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TBI2062-5MG | Yes | 5 MG | $216.00 | |||
TBI2062-25MG | Yes | 25 MG | $864.00 |
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Description
Product Details
Formal Name: 2,3-Epoxy-4-oxo-7,10-dodecadienamide
Molecular Formula: C12H17NO3
Formula Weight: 223.27
CAS Number: 17397-89-6
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to 10 mg/ml) or in Ethanol (up to 10 mg/ml).
Storage: -20°C
Stability: ≥ 2 years.
Applications
Fatty acid biosynthesis inhibitor
Functions
Fatty acid synthase (FAS) inhibitor. Binds to β-keto-acyl-ACP synthase (KAS; IC50=1.5 μM), thus inhibiting protein acylation at concentrations of 45-134 μM. Produces metabolic effects similar to the effects of leptin, but through mechanisms that are independent of, or down-stream of, both leptin and melanocortin receptors. Reduces nutrient-induced insulin release from normal rat islets. Induces apoptosis in human melanoma A-375 cells.
Application Procedures
First dissolved in DMSO (up to 10 mg/ml) or in Ethanol (up to 10 mg/ml), then diluted to aqueous buffer. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.
Additional information
SIZE (mg) | 25 MG, 5 MG |
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