Baicalein, 12-Lipoxygenase inhibitor (TBI2773)
$72.00 – $266.00
12-Lipoxygenase inhibitor
SKU | Stock | SIZE (mg) | Price | Quantity | ||
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TBI2773-100MG | Yes | 100 MG | $72.00 | |||
TBI2773-500MG | Yes | 500 MG | $266.00 |
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Description
Product Details
Formal Name: 5,6,7-Trihydroxyflavone
Molecular Formula: C15H10O5
Formula Weight: 270.24
CAS Number: 491-67-8
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to at least 20 mg/ml)
Storage: -20°C
Stability: ≥ 2 years.
Applications
12-Lipoxygenase inhibitor
Functions
Inhibitor of protein tyrosine kinase in leukemia (CEM) cells. Induces cell cycle arrest and apoptosis. Originally reported as a selective inhibitor of 12-lipoxygenase, baicalein has since been shown to inhibit both 12-LO and 15-LO (IC50=0.64 µM for 12-LO and 1.6 µM for 15-LO). Displays anti-inflammatory activity and inhibits adjuvant-induced arthritis. Also inhibits prolyl oligopeptidase (IC50=36 µM).
Application Procedures
First dissolved in DMSO (up to at least 20 mg/ml), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20°C for up to 1 week.
Additional information
SIZE (mg) | 500 MG, 100 MG |
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