Autogramin-2, GRAMD1A inhibitor (TBI4439)
$126.00 – $495.00
GRAMD1A inhibitor
SKU | Stock | SIZE (mg) | Price | Quantity | ||
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TBI4439-5MG | Yes | 5 MG | $126.00 | |||
TBI4439-25MG | Yes | 25 MG | $495.00 |
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Description
Product Details
Formal Name: t-Butyl 2-[(4-propan-2-yloxybenzoyl)amino]-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridine-5-carboxylate
Molecular Formula: C21H27N3O4S
Formula Weight: 417.50
CAS Number: 2375541-45-8
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to at least 25 mg/ml) or in Ethanol (25 mg/ml)
Storage: -20°C
Stability: ≥ 1 year.
Applications
GRAMD1A inhibitor
Functions
Inhibitor of autophagy (autophagy induced by amino acid starvation IC50 = 270 nM; Rapamycin IC50 = 140 nM) acting via selective targeting of the cholesterol transfer protein GRAM domain-containing protein 1A (GRAMD1A). Autogramin-2 inhibition of GRAMD1A inhibits biogenesis of the autophagosome.
Application Procedures
First dissolved in DMSO (up to at least 25 mg/ml) or in Ethanol (25 mg/ml), then diluted to aqueous buffer. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
Additional information
SIZE (mg) | 25 MG, 5 MG |
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