Ac-Leu-Leu-Nle-CHO (ALLN), Calpain inhibitor (TBI3024)
$90.00 – $338.00
Calpain inhibitor
SKU | Stock | SIZE (mg) | Price | Quantity | ||
---|---|---|---|---|---|---|
TBI3024-5MG | Yes | 5 MG | $90.00 | |||
TBI3024-25MG | Yes | 25 MG | $338.00 |
- Description
- Terms
- Additional information
- Documents
- Reviews (0)
Description
Product Details
Formal Name: Ac-Leu-Leu-Nle-CHO
Alternate Names: Ac-LL-norleucinal
Molecular Formula: C20H37N3O4
Formula Weight: 383.53
CAS Number: 110044-82-1
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to 10 mg/ml) or in Ethanol (up to 5 mg/ml)
Storage: -20°C
Stability: ≥ 1 year.
Applications
Calpain inhibitor
Functions
Cell-permeable, peptide aldehyde inhibitor of calpain I (Ki=190 nM), calpain II (Ki=150 nM), cathepsin L (Ki=0.5 nM) and other neutral cysteine proteases. Inhibits cell cycle progression at G1/S and metaphase/anaphase in CHO cells by inhibiting cyclin B degradation. Inhibits proteolytic degradation of IκBα and IκBβ in RAW macrophages induced with LPS. Blocks AIF-mediated necroptosis. Cell permeable.
Application Procedures
First dissolved in DMSO (up to 10 mg/ml) or in Ethanol (up to 5 mg/ml), then diluted to aqueous buffer. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
Additional information
SIZE (mg) | 25 MG, 5 MG |
---|
Be the first to review “Ac-Leu-Leu-Nle-CHO (ALLN), Calpain inhibitor (TBI3024)”
You must be logged in to post a review.
Reviews
There are no reviews yet.