A77 1726, DHODH inhibitor; Immunosuppresant (TBI1436)
$81.00 – $270.00
DHODH inhibitor; Immunosuppresant
SKU | Stock | SIZE (mg) | Price | Quantity | ||
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TBI1436-5MG | Yes | 5 MG | $81.00 | |||
TBI1436-25MG | Yes | 25 MG | $270.00 |
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Description
Product Details
Formal Name: 2-Cyano-3-hydroxy-N-[4-(trifluoromethyl)phenyl]-2-butenamide
Alternate Names: Teriflunomide
Molecular Formula: C12H9F3N2O2
Formula Weight: 270.21
CAS Number: 108605-62-5
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to 30 mg/ml), or in Ethanol (up to 5 mg/ml with warming).
Storage: -20°C
Stability: ≥ 2 years.
Applications
DHODH inhibitor; Immunosuppresant
Functions
A pyrimidine biosynthesis inhibitor and immunomodulator. Inhibits the mitochondrial dihydroorotate dehydrogenase (DHODH). Leflunomide is rapidly metabolized in human hepatocytes to A77 1726. Cell permeable.
Application Procedures
First dissolved in DMSO (up to 30 mg/ml), or in Ethanol (up to 5 mg/ml with warming), then diluted to aqueous buffer. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
Additional information
SIZE (mg) | 25 MG, 5 MG |
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